Invited/Review Articles
Publications
Invited/Review articles
91. Advances in machine learning-enhanced microfluidic cell sorting
Li, H D, J Bai, X X Ma, L W Li, Y C Liu, X Y Liu, S F Shen , C T Lim, Science Advances, 2025.
90. Advancements and challenges in culturing patient-derived cancer cells for personalized therapeutics
Fu, Y T, B L Khoo, C T Lim, Frontiers in Lab on a Chip Technologies, 4, 1663420, 2025. Abstract
89. Laser-induced graphene for biomedical applications: Innovations in health monitoring and diagnostics
Le, T S D, Tran Y V, Y J Gao, V L Valerio, Z X Ge, C T Lim, Nanoscale Horizons, 2025. Article
88. Wet chemically produced nanomaterials for soft wearable biosensors
Wang, R, G Mao, D Chu, N Nasiri, Y Wang, M Bilek, K-T Yong, W Wong, S Skafidas, J Z Liu, Y Kivshar, M Bhaskaran, Y Lu, B Eggleton, A Ju, Q Shi, N-T Nguyen, C T Lim, W Cheng, Nanoscale Horizons, 10, 1517-1541, 2025. Abstract
87. Toward next-generation smart medical care wearables: when microfluidics meets microneedles
Li, X, S S Wan, T S Pronay, X J Yang, B B Gao, C T Lim, Nanoscale Horizons, 10, 1815, 2025. Abstract
86. Wearable technologies for dental medicine: From flexible sensors to the metaverse
Yu, L T, C T Lim, Translational Dental Research, 1, 3, 100031, 2025.Article
85. Transforming healthcare: Intelligent wearable sensors empowered by smart materials and artificial intelligence
Chen, S, S Fan, Z Qiao, Z Wu, B Lin, Z Li, M A Riegler, M Y H Wong, A Opheim, O Korostynska, K M Nielsen, T Glott, A C T Martinsen, V H Tellle-Hansen, C T Lim, Advanced Materials "Hall of Fame", 37, 21, 2500412, 2025. Article
84. Microfluidics for morpholomics and spatial omics applications
Menon, N V, J Y Lee,T Tang, C T Lim, Lab Chip, 25, 752, 2025. Article
83. Bridging the digital–physical divide using haptic and wearable technologies
Qi, J M, L T Yu, E T Khoo, K W Ng, Y Gao, A W C Kow, J C Yeo, C T Lim, Nature Electronics, 7, 1098, 2024. Abstract
82. Liquid metal functionalization innovations in wearables and soft robotics for smart healthcare applications
Chen, S, S C Fan, H Chan, Z Qiao, J M Qi, Z X Wu, J C Yeo, C T Lim, Advanced Functional Materials, 34, 31, 2309989, 2024. Abstract
81. Advances in flexible electrotactile devices for restoration of biomedical haptic sensation
Jin, Y X, Z X Wu, Y S Zhang, J M Qi, C T Lim, IEEE Transactions on Materials for Electron Devices, vol. 1, 126, 2024. Abstract
80. Artificial intelligence for diabetes care: current and future prospects
Sheng, Bin*, K Pushpanathan*, Z Guan*, Q H Lim*, Z W Lim, S M E Yew, J H L Goh, Y M Bee, C Sabanayagam, N Sevdalis, C C Lim, C T Lim, J Shaw, W Jia, E I Ekinci, R Simó, L-L Lim, H Li, Y-C Tham The Lancet Diabetes & Endocrinology, 12, 8, 569, 2024. Article
79. Wound management materials and technologies from bench to bedside and beyond
Wang, C R, C T Lim, J Wang, D Armstrong, C D Shih, E S San, W Gao, Nature Reviews Materials, 9, 550, 2024. Abstract
78. Insights into the mechanobiology of cancer metastasis via microfluidic technologies
Liang, L F, X Song, H Zhao, C T Lim, APL Bioengineering, 8, 021506, 2024. Abstract
77. Atomic force microscopy in the characterization and clinical evaluation of neurological disorders: current and emerging technologies
She, D T*, M H Nai*, C T Lim, Med-X, 2, 8, 2024. Article
76. Interstitial fluid-based wearable biosensors for minimally invasive healthcare and biomedical applications
Wu, Z X, Z Qiao, S W Chen, S C Fan, Y C Liu, J M Qi, C T Lim, Communications Materials, 5, 33, 2024. Article
75. Liquid metal innovation in wearables and soft robotics for smart healthcare
Chen, S W, S C Fan, H Chan, Z Qiao, J M Qi, Z X Wu, C T Lim, Advanced Functional Materials, 2309989, 2023. Abstract
74. Wearable flexible microfluidic sensing technologies
Chen, S W, Q Zheng, Y Niu, J C Yeo, Y C Liu, J M Qi, S C Fan, X Y Liu, J Y Lee, C T Lim, Nature Reviews Bioengineering, 1, 950-971, 2023. Abstract
73. Technology roadmap for flexible sensors
Luo, Y F, et al, ACS Nano, 17, 6, 5211–5295, 2023. Article
72. Epidermal bioelectronics for management of chronic diseases: materials, devices and systems
Qiao, Z, S W Chen, S C Fan, Z Xiong, C T Lim, Advanced Sensor Research, 2, 8, 2200068, 2023. Article
71. Extracellular matrix mechanobiology in cancer cell migration
Vasudevan, J, K Jiang, J G Fernandez, C T Lim, Acta Biomaterialia, 163, 351-364, 2023. Abstract
70. Cytotoxicity survey of commercial graphene materials from worldwide
Malhotra, R, C E Halbig, Y F Sim, A Kauling, D T W Leong , C T Lim, A C Neto, S Garaj, V Rosa, npj 2D Materials and Applications, 6, 65, 2022. Article
69. Point-of-care diagnostic tests for tuberculosis disease
Hong, J H, H Y Lee, N V Menon, C T Lim, L P Lee, C W M Ong, Science Translational Medicine, 14, 639, 2022. Abstract
68. Flexible wearable sensors for cardiovascular health monitoring
Chen, S W, J M Qi, S C Fan, Z Qiao, J C Yeo,* C T Lim*, Advanced Healthcare Materials, 10, 17, 2100116, 2021. Abstract
67. Microfluidics for liquid biopsies: Recent advances, current challenges, and future directions
Belotti, Y, C T Lim, Analytical Chemistry, 93, 11, 4727-4738, 2021. Abstract
66. Engineering confining microenvironment for studying cancer metastasis
K Jiang, L Liang, C T Lim, iScience, 24, 2, 102098, 2021. Article
65. Microfluidic detection of human diseases: From liquid biopsy to COVID-19 diagnosis
Jiang, K, D S Jokhun, C T Lim, Journal of Biomechanics, Special Issue on Biofluids Mechanics, 117, 110235, 2021. Article
64. Future of health diagnostics
Lim, C T, View, 1, 1, e3, 2020. Article
63. Microfluidic tools for probing micro‐culprits
Lim, S B, , N V Menon, C T Lim, EMBO Reports, 2, 21, e49749, 2020. Abstract
62. Flexible hybrid sensors for health monitoring: Materials and mechanisms to render wearability
Gao, Y, L T Yu, J C Yeo*, C T Lim*, Advanced Materials, 32, 15, 1902133, 2020. Abstract
61. Single-cell analysis of circulating tumor cells: Why heterogeneity matters
Lim, S B, C T Lim, W T Lim, Cancers, 11, 10, 1595, 2019. Article
60. Microfluidics for personalized drug screening of cancer
Menon, N V, S B Lim, C T Lim, Current Opinion in Pharmacology, 48, 155-161, 2019. Abstract
59. Liquid biopsy: one cell at a time
Lim, S B, W D Lee, J Vasudevan, W T Lim, C T Lim, npj Precision Oncology, 3, 23, 2019. Article
58. Advances in technologies for purification and enrichment of extracellular vesicles
Zhang, P, J C Yeo, C T Lim, SLAS Technology: Translating Life Sciences Innovation, 24, 5, 477-488, 2019. Abstract
57. Microfluidic modelling of the tumor microenvironment for anti-cancer drug development
Shang, M L, R H Soon, C T Lim*, B L Khoo*, J Y Han*, Lab on Chip, 19, 369-386, 2019. Abstract
56. Cancer diagnosis: From tumor to liquid biopsy and beyond
V, Ramanathan, R H Soon, P Zhang, K Jiang, C T Lim, Lab on Chip, 19, 11-34, 2019. Abstract
55. Material approaches to active tissue mechanics
Xi, W*, T B Saw, D Delacour, C T Lim*, B Ladoux*, Nature Reviews Materials, 4, 23-44, 2019. Abstract
54. Potential of circulating biomarkers in liquid biopsy diagnostics
Yeo, J C, C T Lim, BioTechniques, 65, 4, 187-189, 2018. Abstract
53. Mechanobiology of tumor growth
Chaudhuri, P K, B C Low, C T Lim, Chemical Reviews, 118, 14, 6499-6515, 2018. Abstract 
52. When stem cells meet graphene: Opportunities and challenges in regenerative medicine
Kenry, C L Wong, K P Loh, C T Lim, Biomaterials, 155, 236-250, 2018.Abstract
51. Exosomes in cancer nanomedicine and immunotherapy: Prospects and challenges
Syn, N L, L Wang, E K H Chow, C T Lim, B C Goh, Trends in Biotechnnology, 35, 7, 665-676, 2017.Abstract
50. Beyond the current state of the syntheses and applications of nanofiber technology
Kenry, C T Lim, Progress in Polymer Science, 70, 1-17, 2017.Article
49. Biocompatibility and nanotoxicity of layered two-dimensional nanomaterials
Kenry, C T Lim, ChemNanoMat, 3, 1, 5-16, 2017.Abstract
48. Emergence of the microfluidic wearable technologies
Yeo, J C, Kenry, C T Lim, Lab on a Chip, 16, 4082-4090, 2016.Abstract
47. Low-dimensional transition metal dichalcogenide nanostructures based sensors
Li, B L, J P Wang, H L Zou, S Garaj, C T Lim, J P Xie, N B Li, D T Leong, Advanced Functional Materials, 26, 39, 7034-7056, 2016.Abstract
46. Emerging flexible and wearable physical sensing platforms for healthcare and biomedical applications
Kenry, J C Yeo, C T Lim, Microsystems & Nanoengineering, 2, 16043, 2016.Abstract
45. Advances in microfluidics in combating infectious diseases
Tay, A, S R Yazdi, A Pavesi, C T Lim, M E Warkiani, Biotechnology Advances, 34, 4, 404-421, 2016.Abstract
44. Single-cell profiling approaches to probing tumor heterogeneity
Khoo, B L, P K Chaudhuri, N Ramalingam, D S W Tan, C T Lim*, M E Warkiani*, International Journal of Cancer, 139, 2, 243-255, 2016.Abstract
43. Mechanobiology of cell migration in the context of dynamic two-way cell-matrix interactions
Kurniawan, N A, P K Chaudhuri, C T Lim, Journal of Biomechanics, 49, 8, 1355-1368, 2016.Abstract
42. Uncovering mechanosensing mechanisms at the single protein level using magnetic tweezers
Le, S, R Liu, C T Lim*, J Yan*, Methods, 94, 13-18, 2016.Abstract
41. Particle-based simulations of red blood cells – A review
Ye, T, N Phan-Thien, C T Lim, Journal of Biomechanics, Special Issue, 2016.Abstract
40. Microfluidics for research and applications in oncology
Parthiv, K C, E W Majid, T Y Jing, Kenry, C T Lim, Analyst, 141, 504-524, 2016.Abstract
39. Rational design of materials interface for efficient capture of circulating tumor cells
Li, Y Q, B K Chandran, C T Lim*, X D Chen*, Advanced Science, 2, 1500118, 2015.Article
38. Mechanobiology of collective cell migration
Saw, T H, S Jain, B Ladoux, C T Lim, Cellular & Molecular Bioengineering, 8, 1, 3-13, 2015.Abstract
37. Circulating tumor cells: Cancer's deadly couriers
Lim, C T, S B Hoon, Physics Today, 67, 2, 26-30, 2014.Abstract
36. Microfluidics for cancer diagnosis
Bhagat, A A S, C T Lim, Asia Pacific Biotech News, 17, 10 &11, 44-47, 2013.Abstract
35. Graphene for smart medical devices
Ang, P K, W C Lee, K P Loh, C T Lim, Asia Pacific Biotech News,17, 1, 34-38, 2013.Abstract
34. Collective Cell Migration: A mechanistic perspective
Vedula, S R K, A Ravasio, C T Lim, B Ladoux, Physiology, 28,6, 370-379, 2013.Abstract
33. Isopore micro/nano engineered membranes– A review
Majid, E W, B L Khoo, A A S Bhagat, J Y Han, C T Lim, H Q Gong, A G Fane, ACS Nano, 7, 3, 1882–1904, 2013.Abstract
32. Tumor dissemination: An EMT affair
Thiery, J P, C T Lim, Cancer Cell, 23, 3, 272-273, 2013.Article
31. Synthesis, optical properties, and chemical-biological sensing applications of one-dimensional inorganic semiconductor nanowires
Kenry, C T Lim, Progress in Materials Science, 58, 5, 705-748, 2013.Abstract
30. Fabrication of large pores in electrospun nanofibrous scaffolds for cellular infiltration: A review
Zhong, S P, Y Z Zhang, C T Lim, Tissue Engineering Part B, 18, 2, 77-87, 2012.Abstract
29. Microfluidics for applications in cell mechanics and mechanobiology
Hou, H W, W C Lee, M C Leong, S Sonam, S R K Vedula, C T Lim, Cellular and Molecular Bioengineering, 4, 4, 591-602, 2011. Abstract
28. Microfluidic devices for blood fractionation
Hou, H W, A A S Bhagat, W C Lee, S Huang, J Y Han, C T Lim, Micromachines, 2, 319-343. 2011.Article
27. Mechanopathology of red blood cell diseases – Why mechanics matters
Lim, C T, A Li, Theoretical & Applied Mechanics Letters, 1, 1, 1-6, 2011.Abstract
26. Advances in experiments and modeling in micro- and nano-biomechanics - A mini review
Long, M, M Sato, C T Lim, J H Wu, T Adachi, Y Inoue, Cellular and Molecular Bioengineering, 4, 3, 327-339, 2011.Abstract
25. Mechanical properties of 1D metal oxide nanostructures
Varghese, B, C H Sow, C T Lim, Special issue on “Nanomechanical Testing”, Nanoscience and Nanotechnology Letters, 2, 4, 268-281, 2010.Article
24. Review on the constitutive models of tumor tissues for computational analysis
Unnikrishnan, G U, V U Unnikrishnan, J N Reddy, C T Lim, Applied Mechanics Reviews, 63, 4, 040801-040807, 2010.Abstract
23. Tissue scaffolds for skin wound healing and dermal reconstruction
Zhong, S P, Y Z Zhang, C T Lim, Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2, 5, 510-25, 2010.Abstract
22. Editorial - Special Issue on “Micro and nanotechnology for biological and biomedical applications”
Lim, C T, J Guck, J Y Han, H Epinosa, Medical and Biological Engineering and Computing, vol. 48, iss 10, 941-943, 2010.Abstract
21. Microfluidics for cell separation
Bhagat, A A S, H Bow, H W Hou, S J Tan, J Y Han, C T Lim, Medical & Biological Engineering & Computing, 48, 10, 999-1014, 2010.Abstract
20. Shape and biomechanical characteristics of human red blood cells in health and disease
Diez-Silva, M, M Dao, J Y Han, C T Lim, S Suresh, MRS Bulletin, 35, 337-408, 2010. (appeared on MRS Bulletin Cover).Article
19. Introduction – Mechanobiology
Lim, C T, A Bershadsky, M P Sheetz, Journal of the Royal Society – Interface, 7, S291-S293, 2010. (appeared on journal cover).Article
18. Computational model of cell positioning: directed and collective migration in the intestinal crypt epithelium
Wong, S Y, K H Chiam, C T Lim, P Matsudaira, Journal of the Royal Society – Interface, 7, Suppl 3, S351-S363, 2010.Abstract
17. Human cell as a structure and machine – An engineering perspective
Vedula, S R K, E Mendoz, W Sun, T S Lim, A Li, Q S Li, C T Lim, IES Journal Part A: Civil and Structural Engineering, 2, 2, 153 – 160, 2009.Abstract
16. Atomistic simulations of inorganic nanowires
Dai, L, V B C Tan, C H Sow, C T Lim, Journal of Nanoscience & Nanotechnology, 9, 1-18, 2009.Abstract
15. Mechanistic insights into physiological functions of cell adhesion proteins using single molecule force spectroscopy
Vedula, S R K, T S Lim, W Hunziker, C T Lim, Molecular & Cellular Biomechanics, 5, 3, 169-82, 2008.Abstract
14. The development of biocomposite nanofibers for tissue scaffolding applications
Zhang, Y Z, C T Lim, JOM, 60, 6, 45-48, 2008.Abstract
13. Biomimetic and bioactive nanofibrous scaffolds from electrospun composite nanofibers : A review
Zhang, Y Z, B Su, J Venugopal, S Ramakrishna, C T Lim , International Journal of Nanomedicine, 2, 4, 623-638, 2008.Abstract
12. Nanotechnology and human diseases
Lee, G Y H, C T Lim, COSMOS, 3, 1, 89-101, 2007.Article
11. Biomechanics approaches to studying human diseases
Lee, G Y H, C T Lim, Trends in Biotechnology, 25, 3, 111-118, 2007.Abstract
10. Single cell mechanics study of the human disease malaria
Lim, C T, Journal of Biomechanical Science & Engineering, 1, 1, 82-92, 2006.Article
9. Experimental techniques for single cell and single molecule biomechanics
Lim, C T, E H Zhou, A Li, S R K Vedula, H X Fu, Materials Science & Engineering C: Biomimetic & Supramolecular Systems, 26, 8, 1278-1288, 2006.Abstract
8. Nanoindentation of teeth - A review
Hairul Nizam, B R, C T Lim, Journal of Experimental Mechanics, 21, 1, 35-50, 2006.Abstract
7. Mechanical characterization of nanofibers – A review
Tan EPS and Lim CT, Composites Science & Technology, 66, 9, 1102-1111, 2006.Abstract
6. Mechanical models for living cells - A review
Lim, C T, E H Zhou, S T Quek, Journal of Biomechanics, 39, 195-216, 2006.Abstract
5. Biophysical approaches for studying the integrity and function of tight junctions
Vedula, S R K, T S Lim, P J Kausalya, W Hunziker, G Rajagopal, C T Lim, Molecular & Cellular Biomechanics, 2, 3, 105-124, 2005.Abstract
4. Recent development of polymer nanofibers for biomedical and biotechnological applications
Zhang, Y Z, C T Lim, S Ramakrishna, Z M Huang, Journal of Materials Science - Materials in Medicine, 16,10,933-946, 2005.Abstract
3. Connections between single-cell biomechanics and human disease states: gastrointestinal cancer and malaria
Suresh, S, J Spatz, J P Mills, A Micoulet, M Dao, C T Lim, M Beil, T Sefferlein, Acta Biomaterialia, 1, 1, 15-30, 2005.Abstract
2. Application of biotechnology, nanotechnology and tissue engineering in cosmetic medicine
Chong, E J, C T Lim, I J Lim, T T Phan, Kosmetische Medizin, 5/6, 212-216, 2005.Abstract
1. Single cell mechanics & its connection to human diseases
Lim, C T, Asia Pacific Biotech, Special Issue - Bioengineering in Asia-Pacific, vol. 9, No. 14, July 2005.Abstract